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DeCS
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Descriptor English:
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Tissue Inhibitor of Metalloproteinases
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Descriptor Spanish:
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Inhibidores Tisulares de Metaloproteinasas
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Descriptor Portuguese:
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Inibidores Teciduais de Metaloproteinases
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Synonyms English:
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Metalloproteinases Tissue Inhibitor
Proteins, TIMP
TIMP Proteins
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Tree Number:
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D12.776.645.875
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Definition English:
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A family of secreted protease inhibitory proteins that regulates the activity of SECRETED MATRIX METALLOENDOPEPTIDASES. They play an important role in modulating the proteolysis of EXTRACELLULAR MATRIX, most notably during tissue remodeling and inflammatory processes. |
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Indexing Annotation English:
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general or unspecified; prefer specifics
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Pharmacological Action:
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Matrix Metalloproteinase Inhibitors
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History Note English:
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98; see TISSUE INHIBITOR OF METALLOPROTEINASES (NM) 1980-97
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Allowable Qualifiers English:
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Record Number:
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33425
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Unique Identifier:
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D019714
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Occurrence in VHL:
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Similar:
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DeCS
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